免费的梯子加速

By sam (June 7, 2018)

MicroRNA Gene Ontology annotations

You might have noticed some additional information on the mature miRNA pages in the last few weeks. See for example: http://mirbase.org/cgi-bin/mature.pl?mature_acc=MIMAT0000123 http://mirbase.org/cgi-bin/mature.pl?mature_acc=MIMAT0000069 The new section “QuickGO function” contains a set of high quality manual annotations of Gene Ontology terms for mature miRNAs, the vast majority of which come from the work of Rachael Huntley et [...]

By sam (March 12, 2018)

miRBase 22 release

After repeated and unreasonable delay, miRBase 22 is finally released. As you might expect with such a long gap, the number of sequences in the database has jumped significantly — by over a third. The vast majority of the increase comes from new microRNA annotations in species not previous represented in the database. Indeed, there [...]

免费的梯子加速

miRBase provides the following services:

The miRBase database is a searchable database of published miRNA sequences and annotation. Each entry in the miRBase Sequence database represents a predicted hairpin portion of a miRNA transcript (termed mir in the database), with information on the location and sequence of the mature miRNA sequence (termed miR). Both hairpin and mature sequences are available for searching and browsing, and entries can also be retrieved by name, keyword, references and annotation. All sequence and annotation data are also available for download.
The miRBase Registry provides miRNA gene hunters with unique names for novel miRNA genes prior to publication of results. Visit the help pages for more information about the naming service.

To receive email notification of data updates and feature changes please subscribe to the miRBase announcements mailing list. Any queries about the website or naming service should be directed at mirbase@manchester.ac.uk.

miRBase is managed by the Griffiths-Jones lab at the Faculty of Biology, Medicine and Health, University of Manchester with funding from the BBSRC. miRBase was previously hosted and supported by the Wellcome Trust Sanger Institute.

免费的梯子加速

If you make use of the data presented here, please cite the following articles in addition to the primary data sources:

miRBase: from microRNA sequences to function.
Kozomara A, Birgaoanu M, Griffiths-Jones S.
Nucleic Acids Res 2019 47:D155-D162

miRBase: annotating high confidence microRNAs using deep sequencing data.
Kozomara A, Griffiths-Jones S.
Nucleic Acids Res 2014 42:D68-D73

miRBase: integrating microRNA annotation and deep-sequencing data.
Kozomara A, Griffiths-Jones S.
Nucleic Acids Res 2011 39:D152-D157

miRBase: tools for microRNA genomics.
Griffiths-Jones S, Saini HK, van Dongen S, Enright AJ.
Nucleic Acids Res 2008 36:D154-D158

miRBase: microRNA sequences, targets and gene nomenclature.
Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ.
Nucleic Acids Res 2006 34:D140-D144

The microRNA Registry.
Griffiths-Jones S.
Nucleic Acids Res 2004 32:D109-D111

The following publications provide guidelines on miRNA annotation:

A uniform system for microRNA annotation.
Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X, Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M, Matzke M, Ruvkun G, Tuschl T.
RNA 2003 9(3):277-279

Criteria for annotation of plant MicroRNAs.
Meyers BC, Axtell MJ, Bartel B, Bartel DP, Baulcombe D, Bowman JL, Cao X, Carrington JC, Chen X, Green PJ, Griffiths-Jones S, Jacobsen SE, Mallory AC, Martienssen RA, Poethig RS, Qi Y, Vaucheret H, Voinnet O, Watanabe Y, Weigel D, Zhu JK.
Plant Cell. 2008 20(12):3186-3190